Choosing Domino is the first step. Now let's finish the journey.
Domino gives your statistical programmers a modern, validated-ready platform for GxP-regulated clinical work. Getting it deployed, integrated, and validated in your environment is where the real work begins — and where KSM comes in.
The platform decision is made. What comes next determines whether it pays off.
Selecting Domino is a significant and well-informed decision. But the path from contract to validated production environment involves infrastructure, integration, documentation, qualification, and organizational change — all moving in parallel. How well that journey is managed shapes how quickly your teams get productive and how defensible your environment is at inspection.
Integration doesn't happen automatically
GitHub, NetApp ONTAP, SSO/IdP, S3 or Azure Blob Storage, firewall configuration — each connection requires configuration, testing, and in many cases, qualification evidence. Every organization's environment is different, and the details matter.
Validation responsibility sits with you
Domino can provide Infrastructure Qualification evidence for their managed cloud platform. Operational and Performance Qualification must be executed by your organization to satisfy GxP requirements. That work needs templates, structure, and someone who has done it before.
Adoption requires more than access
Statistical programmers who've worked in SAS for a decade don't change workflows because a new platform is available. Git is genuinely unfamiliar. New environments are disorienting. The organizations that get value from Domino fastest treat adoption as a people challenge from day one.
The scope is broader than it looks
Environment qualification, compute configuration, standard library setup, training, documentation — it adds up quickly. Building the structure to manage all of it in parallel is itself a project management discipline.
A validated, production-ready SCE in 27 weeks.
KSM's Domino SCE MVP Deployment is a fixed-scope, fixed-timeline implementation built for small to midsize pharmaceutical companies who are ready to move from decision to production.
Validated production environment
A fully qualified Domino deployment — Development, Test, and Production environments — with IQ evidence provided by Domino and OQ/PQ seed kits your team can execute. Every environment meets GAMP 5 and 21 CFR Part 11 requirements.
Baseline documentation package
A User Requirements Specification template, validation plan, and SCE runbook — structured and pre-populated based on our experience across multiple implementations. A proven starting point your QA team can work from, not a blank page.
Compute environments
Five baseline compute environments configured, validated, and ready for statistical programming work. Extensible as your needs evolve.
Git integration
Repository structure, branching strategy, and integration with your chosen Git platform. KSM handles both the technical configuration and the training that makes adoption stick.
Training
Platform training for statistical programmers and system administrators. Designed to build genuine proficiency, not just checkbox completion.
We've walked this path before. Here's what that means for you.
Domino is the SCE engine. KSM's job is integrating it with your environment — your infrastructure, your QMS, your team, your regulatory context. That integration is where implementations succeed or stall.
We've built the connections between Domino and GitHub, NetApp, identity providers, storage platforms, and external systems across multiple engagements. We know where the complexity hides and how to navigate it.
Our team understands the distinction between IQ, OQ, and PQ — and why it matters for your regulatory obligations. We provide the templates and structure. Your quality team executes and owns the evidence. That's the only arrangement that works for an FDA inspection.
Every implementation we run treats programmer adoption as a first-class problem. We use change champions, involve programmers in decisions that affect their daily work, and invest in training that builds real capability. Platforms don't fail — adoption does.
We don't wait until week 27 to show you something working. Delivery is structured so your team has something usable early — a pilot environment, a working workflow, a first study — and each milestone builds on the last.
KSM experts are active contributors to the Domino SCE Coalition and have led validated SCE implementations at pharmaceutical companies ranging from emerging biotech to global enterprise.
What we've learned from doing this, not just advising on it.
Involve QA before you think you need to
QA teams brought in after design decisions are made create friction and rework. The implementations that go smoothly have Quality at the table in week one.
IT and business alignment isn't optional
A technically sound deployment that IT doesn't trust, or that business users won't adopt, is a deployment that hasn't delivered value. Both sides need to be invested from the start.
Git is harder than it looks
For programmers without software development backgrounds, Git concepts are genuinely unintuitive. Plan for meaningful training investment. Don't assume exposure equals proficiency.
Start narrow, expand deliberately
Organizations that try to cover every use case in the first deployment get stuck. Start with one pilot study. Prove the workflow. Then expand. Incremental delivery isn't a compromise — it's how durable implementations are built.
Domino is a platform, not an application
This is the mental model shift that matters most. You're not deploying a tool — you're building an operating environment. The configuration decisions you make in implementation shape every workflow that runs on top of it for years.
This offering is designed for a specific moment in your journey.
Our Domino SCE MVP Deployment is built for organizations that have made the decision to adopt Domino and are ready to move into implementation. It's a structured, scoped path from committed decision to validated production.
If you're earlier in the process — still scoping requirements, evaluating architecture options, or trying to understand what a full implementation would actually involve — our 12-week SCE Scoping Engagement is the right first step. It's how most of our Domino deployments begin.
Explore the 12-week SCE Scoping Engagement →- You have a signed Domino contract or are in final negotiations
- Your requirements are understood and documented
- IT, QA, and business stakeholders are aligned on goals
- Infrastructure access and environment provisioning can begin within weeks